A brief review on bioactivity of platinum therapeutics

Subhajit Mukherjee 1, *, Koyel Misra 1, Suparna Paul 2, Aniruddha Samanta 1 and Sanchita Sarkar 1

1 Department of Basic Science, NSHM Institute of Engineering & Technology, NSHM Knowledge Campus Durgapur, West Bengal-713212, India.
2 Department of Chemistry, NTPC Vindhyachal, Singrauli, Madhya Pradesh-486885, India.
 
Review
International Journal of Science and Research Archive, 2024, 13(02), 1664–1672.
Article DOI: 10.30574/ijsra.2024.13.2.2316
Publication history: 
Received on 18 October 2024; revised on 25 November 2024; accepted on 28 November 2024
 
Abstract: 
The present review includes a brief introduction over deferent platinum anticancer drugs and their mechanism of action as well as their applications and limitations. Various recently studied Pt(II) complexes are also discussed herein. It also highlights the different possible DNA binding mode for a chemical substance as well as intracellular or extracellular platinum-sulfur interactions.
 
Keywords: 
Platinum complexes; Anticancer drugs; Pt-Sulphur adduct; Inorganic metal complexes; DNA binding mechanisms
 
Full text article in PDF: 
 
Copyright information: 

Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0