Levothyroxine management in Hashimoto’s thyroiditis: A comprehensive revie

MONISHA S M, BABIKER BASHIR HAROUN BARAKA *, YADAV V, ANKITH V, ANKITHA GAURAV and NIVEDITHA G

Department of pharmacology, KLE college of pharmacy, Rajajinagar, Bangalore-560010, Karnataka, India.
 
Review
International Journal of Science and Research Archive, 2024, 12(01), 847–853.
Article DOI: 10.30574/ijsra.2024.12.1.0856
Publication history: 
Received on 03 April 2024; revised on 18 May 2024; accepted on 20 May 2024
 
Abstract: 
Hashimoto thyroiditis and hypothyroidism are related thyroid conditions with different aetiologies and clinical manifestations. Insufficient synthesis of thyroid hormones causes hypothyroidism, which may lead to systemic symptoms that impact energy, metabolism, and overall wellness. Thyroid tissue damage mediated by the immune system is the hallmark of the autoimmune thyroid condition known as Hashimoto thyroiditis, which is the most prevalent cause of hypothyroidism. A wide range of symptoms, such as fatigue, weight gain, cold sensitivity, constipation, dry skin, and cognitive impairment, are clinical indications of hypothyroidism and Hashimoto thyroiditis. Thyroid function tests, which measure serum levels of free thyroxine, thyroid-stimulating hormone, and thyroid autoantibodies, must be performed for the diagnosis. Imaging techniques, such ultrasonography, may aid with nodular changes detection and thyroid morphology assessment. The goals of management plans for Hashimoto thyroiditis and hypothyroidism are to stop complications, relieve symptoms, and return the body to normal. The cornerstone of treatment is levothyroxine-based thyroid hormone replacement medication, which is customized for each patient depending on their clinical presentation and thyroid function testing. Dietary restrictions, patient education, and lifestyle changes are essential components of illness management.
 
Keywords: 
Levothyroxine; Hashimoto thyroiditis; Hypothyroidism; Thyroid Hormones; Pathogenesis of hashimoto’s thyroiditis (HT)
 
Full text article in PDF: 
 
Copyright information: 

Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0